The continuous efforts in harnessing sequencing approaches to catalogue genetic variations from populations that have been hitherto underrepresented in genomic research have started unraveling genetic discoveries that have not been previously captured in European populations. The lack of diversity, particularly in neurodegenerative diseases such as Parkinson’s disease, has been recognized. To address this, a trilateral network of Luxembourg-German-Indian Alliance on Neurodegenerative diseases and Therapeutics (Lux-GIANT) was founded in 2018 to pursue trans-ethnic genomic studies in neurodegenerative diseases such as Parkinson’s disease.